The inhibitory effect of watery extracts of Glycyrrhiza Glabra roots on the growth of Candida albicans in comparison with antifungal antibiotics

Abstract

This study was made to evaluate the watery extract both hot and cold of Glycyrrhiza Glabra root on the growing of Candida albicans comparing with Nystatin and Clotrimazol .both cold and hot extract shows inhibitory effect with significant value on (P<0.05) on the growing of Candida albicans comparing with distal water and Nystatin in which the yeast was resistant to that drug . The hot extract in concentration (200 mg/ml) more effective than Clotrimazole , while the cold watery extract did not show the same effect . The hot watery extract was more effective than the cold one .The average of inhibition zone for the first extract on the concentration 50,100,150,200 mg/ml were 11.2,14.6,17.1,21.5 mm, while the average of inhibition zone for the second extract at the same concentrations as following 9.3,21.1,16.6,17.7 mm ,the results shows that the watery extract of Glycyrrhiza Glabra root can be use as an antifungal in the infection with Candida albicans