Genetic study of relationship between resistance of Enterobacter aerugenes to some antibacterial agents and plasmid containinig

Abstract

The present study aimed to determine the relationship between the genetic resistance of Enterobacter aerugenes to some antibacterial agents, and its plasmid containing. For this purpose (70) samples of urine were collected from patients with clinically diagnosed urinary tract infection, there were (15) isolate Enterobacter aerugenes. The Antibiotic susceptibility test was used through using (11) antibiotics and resistance bacteria Enterobacter aerugenes was nitrofurantion ( 100% ) , trimethoprim ( 90 % ) , amikacin (35 % ) , norfloxacin (45% ) , cefotaxime (50 %) , ceftriaxon (38 %) , chloramphenecol (64 % ) , imipenem (10 % ) , doxocyclin (80 % ) , gentamycin (58 % ) and ciprofloxacin (53 %) . The data indicated the increase infection of urinary tract infection that caused by Enterobacter aerugenes . There are two antibiotics nitrofurantion and trimethoprim must not use to treatment against Enterobacter aerugenes in the future because the bacteria gave high resistance these antibiotics. The resistance of Enterobacter aerugenes to antibiotics used in this study linked with increasing bounds of plasmid.