Study of physiological and cytogenetic changes to males patients with diabetic mellitus type2 by used the body mass index

Abstract

The study included 20 patients and have ranged in age from (30-75 years), compared with a control groups which included 12 individual, with ages have ranged from (38-70) years. The study investigate biochemical parameters included measuring the levels of each of (Total Cholesterol , Triglyceride , low-density lipoproteins, high density lipoproteins , lipoproteins very low density, and measuring hormone levels Testosterone, and estimate the damage in DNA and measuring the Micronucleus and Mitotic index and analysis of Comet Assay in lymphocytes for patients and control: The results of our study showed a high change (P< 0.05) in the level of each of (cholesterol, triglycerides , low-density lipoproteins , lipoproteins very low density , and the low significant (P< 0.05) level of high density lipoproteins and of the Testosterone hormone .The results showed a high significant (P< 0.05) in the Mitotic index and Micronucleus , appearance of numbers low in the number the Nuclear division index, where results showed a high significant (P< 0.05) in damage to the DNA molecule by comet assay when compared with control group.