Study of some physiological changes of blood in hepatitis B & C patients

Abstract

Hepatitis B and hepatitis C was blood –borne viruses. The liver is the second largest organ of the body (after the skin) and the largest vital gland in the body. One hundred fifty four patients were taken for this study 79 patients undergoing hepatitis B,50 males with age range(20-49)years and 29 females with age range(20-49)years, and 75 patients undergoing hepatitis C ,50 males with age range(20-59) years and25 females with age range(20-49)years and 50 healthy control,25 males with age range (20-45) years, and 25 females with age range (20-43) years. The present results appear significant decrease (P < 0.01) in the mean value Hb, PCV, WBCs and PLT in males and hepatitis C but non-significant in hepatitis B when compared with healthy control .Also the results appear significant decrease (P < 0.01) in the mean value Hb, PCV, WBCs and PLT in females hepatitis C but non-significant in females hepatitis B when compared with control group. Whereas the results of biochemical tests appear significant increase (P < 0.01) in the mean value ALT,AST,ALP,total bilirubin,direct and indirect in males hepatitis B and C compared with healthy control.Also the same biochemical parameters was significant increase (P < 0.01) in the mean value ALT, AST, ALP, total bilirubin ,direct and indirect in females hepatitis B and C compared with healthy control group.The of NBT appear significant decrease(P < 0.01) in the mean value of neutrophils(+) in males and females hepatitis B and C compared with healthy control group. The aims of the study is to study of biochemical Parameters, Hematological Parameters and Phagocytic activity by using Nitroblue tetrazolium stain (NBT) in patients with hepatitis B and C compared the results with healthy people.