Evaluation of Some Biochemical Indices in Chronic Kidney Failure (CKF) Patients in Pre- and Post-Haemodialysis in Wasit Province

Abstract

The present study aimed for evaluation of some biochemical indices (ALT, AST, ALP, total bilirubin, albumin, and uric acid) in pre-haemodialysis and post-haemodialysis, in sera of chronic kidney failure (CKF) patients, to compare their results between them and with control groups. For this purpose, a total of 72 CKF patients as well as 72 healthy people, from both sexes, were submitted for blood samples collection and biochemical indices testing in dialysis unit at Wasit province. From each patient, two blood samples have been drained, the first in pre-haemodialysis period and the second post-haemodialysis period, while the blood samples of healthy people have been used as a control group. The results of pre-haemodialysis were revealed on a noticeable increasing in concentrations of ALT, ALP, and uric acid; with decreasing a totally bilirubin levels if compared with control group, while, the differences in AST and albumin results were not showed. Also, the results of post-dialysis were reported a marked elevation in concentrations of ALT, AST, ALP, and total bilirubin; but they did not detect in albumin and uric acid levels, when compared to control group. In addition, the results of post-haemodialysis, when compared with pre-haemodialysis results, appeared to have an elevation in concentrations of ALT, AST, ALP, and total bilirubine; while, they reported an obvious reduction in uric acid.