High Prevalence of Coagulase Negative Staphylococci Among Outpatient Women with Acute Urinary Tract Infection

Abstract

Urinary tract infections (UTIs) caused by coagulase-negative staphylococci (CoNS) represent a major public health challenge worldwide. The current research focused on the isolation and identification of CoNS' species from pregnant and nonpregnant outpatient women with acute UTI and measuring their antibiogram. From a total number of 137 positive cultures, a 111 (81.0 %) were identified as Staphylococcus spp., a 70.2 % of them were CoNS. Eight species of CoNS were detected by two multiplex PCR protocols. Staphylococcus epidermidis was the most prevalent (36/137: 26.2 %), followed by S. haemolyticus (26/137: 18.9 %). S. capitis was also isolated (1/137: 0.7 %). Whereas 10.9 % of CoNS remained unidentified. An antibiogram assay was conducted. High resistance was against penicillin (84.6 %) and cefoxitin (60.2 %). Resistance to trimethoprim, gentamicin, norfloxacin, ciprofloxacin, and nitrofurantoin were: 37.1 %, 33.3 %, 20.5 %, 16.6 %, and 8.9 %, respectively. However, there are high prevalence of CoNS as uropathogens. Nitrofurantoin, ciprofloxacin, and norfloxacin are a suitable for the treatment of UTIs caused by CoNS.