Study of Human Immunoglobulin G(IgG) and Immunoglobulin M(IgM) in COVID-19 Patients with Chronic Diseases and Non-Chronic Diseases

Abstract

Coronavirus disease 2019 (COVID-19), an infectious respiratory disease caused by the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV2) in Wuhan, Hubei Province, China in December 2019. The current article study levels of IgG and IgM for the body against COVID-19 in patients with and without chronic diseases. Also, shed light on the influence of chronic diseases in immune response by using ELISA. The results showed that no significant importance for the level of IgG in COVID-19 patients with chronic diseases compared with patients without chronic diseases. While there was a significant increase in IgM levels in COVID-19 patients of chronic diseases compared with control of chronic diseases. In addition, according to age groups, results show that IgM levels can be much higher in patients with chronic diseases compared to patients without chronic diseases. IgM levels may also vary depending on age, it’s gave significant importance in age range older than 55 years. However, no significant difference in level IgG in patients of chronic diseases compared with patients without chronic diseases. On the other hand, the level of IgM in COVID-19 patients with chronic diseases significant higher compared with control.