Antifungal Activity of Ginger Extract Against Aspergillus Spp In Vitro Study

Abstract

Zingiber officinale is widely used in traditional Asian medicine. Ginger may be used medicinally to treat a variety of ailments. Ginger contains active ingredients such as phenolics (like zingerone) and sesquiterpenoids (like gingerol and shogaol). That shows antibacterial properties against a variety of bacteria, fungus, and parasites. Ginger has numerous medicinal uses for a wide range of illnesses, such as growth problems, atherosclerosis, TB, vomiting, rubella, and inflammatory diseases. To evaluate the anti-fungal activity of Z. officinale against Aspergillus fumigatus Results of the study indicate that Z. officinale extracts, both aqueous and ethanolic, have strong antifungal activity against the A. fumigatus. The concentration and kind of extract affected the antifungal action.  The alcoholic extract worked better than the aqueous extract. Possibly because ethanol extracts contain stronger antifungal compounds. Antifungal effectiveness was evaluated in the current study using the poisoned food method. Results of the "disc diffusion method" on the growth of A. fumigatus using ethanolic and aqueous extracts of Z. officinale. The inhibition zones for the tested fungus were (28.6 mm) at a concentration of 25 % ethanolic extracts and (16.2 mm) at a concentration of 25 % aqueous extracts when compared to the control. The result demonstrates that ethanolic extracts were more effective than aqueous extracts, and the effect increased with increased concentration.