Determination of Ephedrine Hydrochloride in its Pharmaceutical Preparations by using molecular absorption (UV-Visible) technique

Abstract

The presented paper aims at using an innovative analytical method to determine the drug ephedrine hydrochloride (EPH), (Usually used for treating different diseases like asthma) in some pharmaceutical preparations using molecular absorption techniques (UV-Visible). Chelate complex is prepared through the reaction between EPH and Co (II). Determination of ephedrine is done as a EPH – Co (II) after extraction by chloroform at λ max 389 nm, and the analytical results are obtained as follows, metal to legend (2:1). Linear dynamic range (1-80g/ml) for EPH, (RSD%=0,303), D.L= (0, 94 g/ml), Sandell's sensitivity (S=0.0135), (Erel. %=0, 039), (Rec. %=100, 039)